tag:blogger.com,1999:blog-126852961571725269.post5604932438189177207..comments2024-02-24T06:25:59.743-08:00Comments on The Spine Blogger: Biodegradable Magnesium, Could We be looking into the Future of Spinal Implants?Musculoskeletal Manhttp://www.blogger.com/profile/14873819014357051373noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-126852961571725269.post-82004561827568486512010-01-06T11:23:57.100-08:002010-01-06T11:23:57.100-08:00I don't think the FDA will be the big problem ...I don't think the FDA will be the big problem here, especially for ortho applications. First, the cardio industry will demonstrate (or not) if resorbable metal is safe through their current trials of resorbable metal stents. Second, the type of "debris" from wear and resorption are totally different. The particle size is orders of magnitude different, and the mechanism of breakdown is totally different (mechanical vs. chemical). Safety with respect to "metal" doesn't worry me here. I don't think you'd want to overshoot on applications--stick to fixation (probably outside of spine).Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-126852961571725269.post-11740566581154463382010-01-06T08:47:12.264-08:002010-01-06T08:47:12.264-08:00Metallic Glasses hold great promise - really, but ...Metallic Glasses hold great promise - really, but they are not strong enough “Kryptonite” to defeat the FDA/VC's/Insurers/Providers... sadlyAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-126852961571725269.post-84291022353616525322010-01-05T18:44:13.329-08:002010-01-05T18:44:13.329-08:00Each person has a different rate of metabolizing r...Each person has a different rate of metabolizing resorbable material hence sterile abcess formation.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-126852961571725269.post-16377107392782037102010-01-05T18:10:39.450-08:002010-01-05T18:10:39.450-08:00Ever seen a pic from a MOM THA pseudotumor?Ever seen a pic from a MOM THA pseudotumor?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-126852961571725269.post-81325126727225147282010-01-05T14:38:54.387-08:002010-01-05T14:38:54.387-08:00Cost containment and health care reform are going ...Cost containment and health care reform are going to set back innovation in the medical area quite significantly. Interesting ideas will not be moved on for lack of ability to get them past the regulatory and reimbursement hurdles. Look at the investments make in disc arthroplasty as an example. Some big companies got burned and this will have a negative impact on future endeavors.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-126852961571725269.post-39910411990502208012010-01-05T13:26:12.994-08:002010-01-05T13:26:12.994-08:00Sounds innovative.
Doesnt both Danek and Depuy ha...Sounds innovative.<br /><br />Doesnt both Danek and Depuy have resorable cervical plates made of some sort of poly mix?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-126852961571725269.post-54965751781582507272010-01-05T12:08:31.606-08:002010-01-05T12:08:31.606-08:00Good luck getting this through the FDA. FDA has a...Good luck getting this through the FDA. FDA has a problem with metal wear debris and the residual effects. So, some questions, what would be the particulate size, where would they travel in the blood stream, how much is too much, what is the rate of degradation, does it change over time or by size of material or location in the body, what effect does sterilization and oxidation have on the magnesium, etc.? The debris from a small screw is probably equivalent to the amount of debris from a MOM hip over 10 years. So, if multiple screws and a plate are used in a fx healing scenario, what would the long-term effect of that be?<br /><br />Last, this is essentially accelerating the rusting process of a metal. How would a patient feel about this?Anonymousnoreply@blogger.com